The Coflore® Agitated Cell Reactor (ACR) is AM Technology’s Laboratory-Scale Flow Reactor. The Coflore ACR is an actively mixed, bench-top flow reactor, used within a laboratory environment for developing and optimizing scalable flow chemistry solutions, or for when limited quantities of reactants or material are available or required. Processes designed and optimized in the Coflore ACR can be scaled up to multi-kilogram and multi-ton production in the Coflore ATR and Coflore RTR flow reactors.
The Coflore ACR is a mechanically agitated flow reactor with a reactor channel divided into ten stages, operating as ten CSTRs in series for plug flow performance. Coflore technology provides efficient active-mixing even at very low flow rates, providing versatility for handling a variety of liquid, liquid-liquid, solid-liquid, liquid-gas, and solid-liquid-gas reaction mixtures, including dense slurries.
The Coflore ACR flow reactor is ideal for establishing and developing continuous processes prior to scale up, or when only limited quantities of material are available or required. Processes developed on an ACR platform have a straight-forward path to scale up via the larger volume Coflore ATR and Coflore RTR pilot and production scale flow reactors.
The ACR-100 cell block is comprised of ten inter-connected reaction stages in series and block is positioned within the ACR reactor block assembly, which is in turn mounted onto the ACR agitating platform within the ACR control cabinet.
The ACR-100 cell block is ideally suited to processing homogeneous and multi-phase mixtures, including dense slurries.
The Coflore ACR Counter-Current Cell Block (ACX-100) is used for counter-current operations, including counter-current extraction, for multiple phases flowing in opposite directions along the reaction path. The ACX-100 replaces the ACR-100 cell block inside the ACR reactor block assembly.
Continuous counter-current extractors give higher extraction efficiency with lower solvent usage when compared to standard co-current configurations.